Multiplicity in systematic reviews and meta-analysis: Dealing with multiple source multiple outcomes

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Date
2020-02-21 (Creation date: 2020-02-21)
Main contributor
Evan Mayo-Wilson
Summary
Publication and reporting bias are well-documented in the scientific literature. Increased data and code sharing, and access to other sources of information such as Clinical Study Reports (CSRs), address concerns about the non-reproducibility of individual studies. Ironically, greater transparency has given rise to new problems. That is, systematic reviewers and meta-analysts can choose from among dozens of effect sizes that could be included in their analyses. Initiatives that increase validity and reproducibility in individual studies also create opportunities for bias in research synthesis and clinical guideline development. Scientists could adopt new methods to avoid cherry-picking at all stages of research and evidence synthesis.
Publisher
IU Workshop in Methods
Collection
Workshop in Methods
Unit
Social Science Research Commons
Related Item
Accompanying materials in IUScholarWorks 
Notes

Performers

Dr. Evan Mayo-Wilson is an Associate Professor in the Department of Epidemiology and Biostatistics at the Indiana University School of Public Health-Bloomington.

Access Restrictions

This item is accessible by: the public.